F093 From Blisters to Breakthroughs: Updates in Epidermolysis Bullosa
DESCRIPTION
Join our session to learn essential care practices for epidermolysis bullosa (EB) patients. Explore newly FDA-approved treatments and treatments in the pipeline, such as topical gene therapy, gene therapy grafts, and anti-inflammatory treatments. Hear firsthand from an EB parent about their experiences with these innovative treatments and living with EB. Gain invaluable insights to enhance your care for EB patients in your practice.
LEARNING OBJECTIVES
Describe the types of Epidermolysis Bullosa (EB) and their management
Assess novel therapies for epidermolysis bullosa and appropriate scenarios for use.
Appreciate the patient perspective of living with epidermolysis bullosa
SCHEDULE
1:00 PM
Introduction to EB
Maria Gnarra Buethe, MD, PhD, FAAD
1:05 PM
Itch in EB
Amy S. Paller, MD, FAAD
1:20 PM
Anti-Inflammatory Treatments in EB
Dedee F. Murrell, MD, FAAD
1:35 PM
Q&A
Maria Gnarra Buethe, MD, PhD, FAAD, Dedee F. Murrell, MD, FAAD, Amy S. Paller, MD, FAAD
1:37 PM
EB Skin Care Tips
Laura Levin, MD, FAAD
1:52 PM
Multidisciplinary Care of the EB Patient
Anna Lee Bruckner, MD, FAAD
2:07 PM
Q&A
Anna Lee Bruckner, MD, FAAD, Laura Levin, MD, FAAD
2:09 PM
Ex Vivo Gene Therapy in EB
Emily S. Gorell, DO, MS, FAAD
2:24 PM
In Vivo Gene Therapy in EB
M. Peter Marinkovich, MD, FAAD
2:39 PM
Q&A
Emily S. Gorell, DO, MS, FAAD, M. Peter Marinkovich, MD, FAAD
2:41 PM
Parent and Advocate Perspective
Heather Fullmer
2:56 PM
Q&A
Heather Fullmer
DIRECTOR
Emily S. Gorell, DO, MS, FAAD
SPEAKERS
Anna Lee Bruckner, MD, FAAD
Maria Gnarra Buethe, MD, PhD, FAAD
Children's Hospital of Orange County/University of California Irvine
Heather Fullmer
Laura Levin, MD, FAAD
M. Peter Marinkovich, MD, FAAD
Dedee F. Murrell, MD, FAAD
Amy S. Paller, MD, FAAD
HANDOUTS
DISCLOSURES
Anna Lee Bruckner, MD, FAAD
Abeona Therapeutics – Advisory Board(Honoraria); Castle Creek Pharmaceuticals – Investigator(Grants/Research Funding); Chiesi Farmaceutici – Advisory Board(Honoraria); RHEACELL – Investigator(Grants/Research Funding); TWi Biotechnology, Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding);
Maria Gnarra Buethe, MD, PhD, FAAD
No financial relationships exist with ineligible companies.
Heather Fullmer
No financial relationships exist with ineligible companies.
Emily S. Gorell, DO, MS, FAAD
Abeona Therapeutics – Advisory Board(Honoraria), Consultant (1099 relationship)(Fees); Amryt Pharma – Advisory Board(Honoraria); Chiesi – Advisory Board(Honoraria); Krystal Biotech, Inc – Advisory Board(Honoraria), Consultant(Honoraria);
Laura Levin, MD, FAAD
No financial relationships exist with ineligible companies.
M. Peter Marinkovich, MD, FAAD
No financial relationships exist with ineligible companies.
Dedee F. Murrell, MD, FAAD
AbbVie – Investigator(Grants/Research Funding); Actavis – Speaker/Faculty Education(Honoraria); Almirall – Consultant(Honoraria); Alumis – Investigator(Fees); Amgen – Investigator(Fees); Amicus Therapeutics – Advisory Board(Honoraria); Amryt Pharma – Investigator(Fees); Anacor Pharmaceuticals, Inc. – Investigator(Grants/Research Funding); Apogee Therapeutics – Investigator(Fees); Arena Pharmaceuticals – Investigator(Grants/Research Funding); arGEN-X – Investigator(Fees); Ascent Pharmaceuticals – Speaker(Honoraria); Attovia Therapeutics – Investigator(Fees); Bambusa Therapeutics Inc – Advisory Board(Fees); BMS – Investigator(Fees); Castle Creek Pharmaceuticals – Consultant(Fees); Chiesi Farmaceutici – Advisory Board(Fees); CSL – Speaker(Honoraria); Delfin Technology – Investigator(Equipment); Eli Lilly and Company – Advisory Board(Honoraria); Evelo Biosciences, Inc. – Investigator(Fees); Galderma Laboratories, L.P. – Investigator(Grants/Research Funding), Investigator(Other Financial Benefit); Incyte – Investigator(Fees); Johnson & Johnson – Investigator(Grants/Research Funding); Krystal Biotech, Inc – Other(No Compensation Received); L'Oreal – Speaker(Fees); Leo Pharma Inc – Speaker/Faculty Education(Honoraria); Medimmune – Investigator(Fees), Investigator(Grants/Research Funding); Nektar Therapeutics – Investigator(Fees); Novartis Pharmaceuticals Corp. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Ono – Advisory Board(Fees); Pfizer Inc. – Investigator(Grants/Research Funding); Pierre Fabre Dermo-Cosmétique US – Speaker(Honoraria); Principia Biopharma Inc – Consultant(Honoraria); RAPT Therapeutics – Advisory Board(Fees); Regeneron Pharmaceuticals Inc – Advisory Board(Fees); RHEACELL – Data Safety Monitoring Board(Fees); Roche Laboratories – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Sanofi – Advisory Board(Fees), Investigator(Fees), Investigator(Grants/Research Funding); Schering-Plough Corporation – Investigator(Grants/Research Funding); Shire – Advisory Board(Honoraria), Investigator(Grants/Research Funding); TWi Biotechnology, Inc. – Advisory Board(Fees), Investigator(Fees); UCB – Investigator(Fees); UpToDate – Other(Fees);
Amy S. Paller, MD, FAAD
AbbVie – Data Safety Monitoring Board(Honoraria), Investigator(Grants/Research Funding); Abeona Therapeutics – Data Safety Monitoring Board(Honoraria); Arcutis Biotherapeutics – Consultant (1099 relationship)(Honoraria); BioCryst Pharmaceuticals, Inc. – Consultant (1099 relationship)(Honoraria), Data Safety Monitoring Board(Honoraria); BioMendics, LLC – Investigator(Grants/Research Funding); Boehringer Ingelheim – Consultant(Honoraria); Castle Creek Pharmaceuticals – Consultant (1099 relationship)(Honoraria); Chiesi Farmaceutici – Consultant (1099 relationship)(Honoraria); Daiichi Sankyo – Data Safety Monitoring Board(Honoraria); Dermavant Sciences, Inc. – Investigator(Grants/Research Funding); Eli Lilly – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Galderma – Data Safety Monitoring Board(Honoraria); Incyte Corporation – Investigator(Grants/Research Funding); Johnson & Johnson Innovative Medicine – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Krystal Biotech, Inc – Consultant(Honoraria); L'Oréal France – Consultant (1099 relationship)(Honoraria); Leo Pharma Inc – Consultant(Honoraria); MoonLake Immunotherapeutics – Consultant (1099 relationship)(Honoraria); Pelthos Therapeutics – Consultant (1099 relationship)(Honoraria); Quoin Pharmaceuticals Ltd – Consultant (1099 relationship)(Honoraria); Regeneron – Consultant(Honoraria), Investigator(Grants/Research Funding); Sanofi Genzyme – Consultant(Honoraria); UCB – Investigator(Grants/Research Funding);