F082 Itch
DESCRIPTION
Chronic pruritus, arising idiopathically or in association with cutaneous or systemic disease, may be incapacitating. This session is meant for the clinician who wants to understand how itch arises and how to approach itch management in different clinical scenarios, including but not limited to itch resulting from allergic, systemic, and neuropathic disorders. Expert itch clinicians will explain what’s new in itch pathophysiology and will communicate their experience in the diagnosis and management of challenging itches, including neuropathic itch, prurigo nodularis, urticarial and atopic disorders. Novel and pipeline therapies and devices for the management of chronic itch will be discussed.
LEARNING OBJECTIVES
Categorize different types of chronic itch and utilize appropriate diagnostic tests in the evaluation of patients suffering form chronic pruritus.
Incorporate immunomodulators, neuromodulators and alternative therapies into the management of patients with chronic itch.
Describe new or pipeline agents to treat chronic itch.
SCHEDULE
9:00 AM
Introduction to Itch
Sarina Elmariah, MD, FAAD
9:05 AM
Unmasking the Hidden Itch: Neuro-Immune Insights in Genital Pruritus
Gil Yosipovitch, MD
9:30 AM
Updates in Itch Pathophysiology
Brian S Kim, MD, FAAD
9:55 AM
Lessons from the Itch Playbook
Shawn Kwatra, MD, FAAD
10:20 AM
Tackling Itch in Atopic Dermatitis
Jonathan I. Silverberg, MD, PhD, MPH, FAAD
10:45 AM
Questions & Answers
DIRECTOR
Sarina Elmariah, MD, FAAD
SPEAKERS
Brian S Kim, MD, FAAD
Shawn Kwatra, MD, FAAD
Jonathan I. Silverberg, MD, PhD, MPH, FAAD
Gil Yosipovitch, MD
DISCLOSURES
Sarina Elmariah, MD, FAAD
Eli Lilly – Other(Honoraria); Galderma Laboratories, LP – Advisory Board(Honoraria); Pfizer Inc. – Advisory Board(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria);
Brian S Kim, MD, FAAD
23andMe – Consultant (1099 relationship)(Fees); AbbVie – Consultant(Fees); Almirall – Advisory Board(Honoraria); Amagma Therapeutics – Consultant(Fees); Amgen – Consultant (1099 relationship)(Fees); Arcutis Biotherapeutics – Consultant (1099 relationship)(Fees); AstraZeneca – Consultant (1099 relationship)(Fees); Bellus Health – Advisory Board(Honoraria); Blueprint Medicines – Board of Directors(Honoraria); BMS – Consultant(Honoraria); Boehringer Ingelheim – Advisory Board(Honoraria); Cara Therapeutics – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Clexio – Consultant (1099 relationship)(Fees); Daewoong Pharmaceuticals – Consultant(Fees); Eli Lilly and Company – Advisory Board(Honoraria); Escient Pharmaceuticals, Inc – Consultant (1099 relationship)(Fees); Evommune, Inc. – Consultant (1099 relationship)(Fees); Galderma – Consultant (1099 relationship)(Fees); Genentech, Inc. – Consultant (1099 relationship)(Fees); GlaxoSmithKline – Consultant (1099 relationship)(Fees); Granular Therapeutics – Consultant(Fees); Guidepoint Global, LLC – Consultant(Fees); Incyte Corporation – Consultant(Fees); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria); Klirna – Founder(Stock); Klirna Biotech, Inc. – Founder(Stock); Leo Pharma Inc. – Consultant(Fees), Investigator(Grants/Research Funding); Locus Biosciences – Stockholder(Stock); Micreos – Consultant (1099 relationship)(Fees); Novartis – Advisory Board(Honoraria); Nuogen Pharma – Founder(Stock); OM Pharma – Consultant(Fees); Pfizer Inc. – Consultant(Honoraria); Recens Medical – Consultant(Fees); Sanofi – Consultant(Fees); Sanofi Genzyme – Consultant(Fees); Sanofi/Regeneron – Advisory Board(Honoraria); Septerna – Consultant (1099 relationship)(Fees); Shaperon – Consultant(Fees); Teva Pharmaceuticals USA – Advisory Board(Fees); Trevi Therapeutics – Consultant(Fees); VeraDermics Inc. – Investigator(Fees);
Shawn Kwatra, MD, FAAD
AbbVie – Consultant(Honoraria); Amgen – Advisory Board(Honoraria); Arcutis Biotherapeutics – Advisory Board(Honoraria); Castle Biosciences, Inc – Consultant(Honoraria); Galderma – Investigator(Grants/Research Funding); Galderma USA – Consultant(Honoraria); Incyte Corporation – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Johnson and Johnson – Advisory Board(Honoraria); Leo Pharma Inc – Advisory Board(Honoraria); Novartis – Consultant(Honoraria); Pfizer Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Regeneron – Advisory Board(Honoraria); Sanofi – Advisory Board(Honoraria), Investigator(Grants/Research Funding);
Jonathan I. Silverberg, MD, PhD, MPH, FAAD
AbbVie – Consultant(Honoraria), Investigator(No Compensation Received), Speaker(Honoraria); Aldena Therapeutics – Consultant(Fees); Amgen – Consultant(Fees); AOBiome, LLC – Consultant(Fees); Apollo Therapeutics Ltd – Consultant (1099 relationship)(Fees); Arcutis, Inc. – Consultant(Fees), Speaker(Fees); Asana Biosciences, LLC – Consultant(Honoraria); Attovia – Advisory Board(Fees); Attovia Therapeutics – Advisory Board(Fees); Biosion – Consultant(Fees); Bodewell – Consultant(Fees); Boehringer Ingelheim – Advisory Board(Fees); Castle Biosciences – Consultant(Fees); Connect Biopharma LLC – Consultant(Fees); Corrona, Inc. – Advisory Board(Honoraria); Dermavant Sciences – Consultant(Fees); Eli Lilly and Company – Consultant(Honoraria), Investigator(No Compensation Received), Speaker(Fees); Galderma – Speaker(Fees); Galderma Research & Development, LLC – Consultant(Honoraria); GlaxoSmithKline – Consultant(Honoraria), Investigator(No Compensation Received); Incyte Corporation – Consultant(Honoraria), Speaker(Honoraria); Inmagene Biopharmaceuticals – Consultant (1099 relationship)(Fees); Leo Pharma Inc – Advisory Board(Honoraria), Speaker(Honoraria); Leo Pharma Inc. – Investigator(Honoraria); Maui Derm – Speaker(Fees); Nektar Therapeutics – Consultant (1099 relationship)(Fees); Novartis – Consultant(Fees); Pfizer Inc. – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Fees); RAPT Therapeutics – Advisory Board(Fees); Regeneron – Consultant(Honoraria), Investigator(No Compensation Received), Speaker(Honoraria); Sanofi – Consultant(Grants/Research Funding); Sanofi Genzyme – Speaker(Honoraria); Shaperon – Consultant(Fees); TARGET Pharma – Advisory Board(Honoraria), Investigator(No Compensation Received); UCB – Consultant (1099 relationship)(Fees); Union Therapeutics – Consultant(Fees); UpToDate – Other(Fees);
Gil Yosipovitch, MD
AbbVie – Advisory Board(Honoraria); Arcutis, Inc. – Advisory Board(Honoraria); Cara Therapeutics – Advisory Board(Honoraria); CeraVe – Advisory Board(Honoraria); Eli Lilly – Investigator(Fees), Investigator(Grants/Research Funding); Eli Lilly and Company – Advisory Board(Honoraria); escient – Investigator(Fees), Investigator(Grants/Research Funding); Galderma – Advisory Board(Honoraria); Galderma Laboratories, L.P. – Consultant(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); GSK – Advisory Board(Honoraria); Kamari Pharma – Consultant(Fees); Kiniksa Pharmaceuticals, Ltd. – Investigator(Grants/Research Funding); Maruho Co., Ltd – Speaker/Faculty Education(Fees); Novartis – Consultant(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); Pfizer Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Pierre Fabre – Consultant(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); Vifor Pharma – Consultant(Fees);