F074 Challenging Skin Disorders of Hands and Feet
DESCRIPTION
Hands and feet skin disorders have a huge impact on quality of life and are often a diagnostic and therapeutic challenge. This session will review clinical presentation, management and treatment of challenging hand and foot disorders including psoriasis, palmoplantar pustulosis, vitiligo, chronic hand eczema, recurrent actinic keratoses and peri-ungual warts. Recent developments in etiopathogenesis and challenging diagnoses of skin disorders involving hands and feet will also be reviewed and discussed.
LEARNING OBJECTIVES
Manage challenging cases of skin diseases involving hands and feet.
Select the best treatment options for vitiligo, psoriasis, pustulosis, eczema, periungual warts and actinic keratoses affecting hands and/or feet.
SCHEDULE
9:00 AM
Hand and foot eczema: recent advances on etiopathogenesis
Emma Guttman, MD, PhD, FAAD
9:15 AM
Treatment of hand and foot eczema
Robert Bissonnette, MSc, MD, FAAD
9:30 AM
Treatment of hand and foot psoriasis
Bruce Elliot Strober, MD, PhD, FAAD
9:45 AM
Palmoplantar pustulosis: workup and treatment
Thierry Passeron, MD, PhD
10:00 AM
Hand vitiligo: a therapeutic challenge
Iltefat H. Hamzavi, MD, FAAD
10:15 AM
Treatment options for recalcitrant periungual warts
Kendall Billick, MD, FAAD
10:30 AM
Treatment of recurrent actinic keratoses on the back of the hands
Rolf-Markus Szeimies, MD, PhD, IFAAD
10:45 AM
Palmoplantar diagnostic challenges
Mark Lebwohl, MD, FAAD
DIRECTOR
Robert Bissonnette, MSc, MD, FAAD
SPEAKERS
Kendall Billick, MD, FAAD
Emma Guttman, MD, PhD, FAAD
Iltefat H. Hamzavi, MD, FAAD
Mark Lebwohl, MD, FAAD
Thierry Passeron, MD, PhD
Bruce Elliot Strober, MD, PhD, FAAD
Rolf-Markus Szeimies, MD, PhD, IFAAD
DISCLOSURES
Kendall Billick, MD, FAAD
No financial relationships exist with ineligible companies.
Robert Bissonnette, MSc, MD, FAAD
AbbVie – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Aclaris Therapeutics Inc. – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Aldena Therapeutics – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Almirall – Consultant (1099 relationship)(Honoraria), Other(Grants/Research Funding); Alumis – Investigator(Grants/Research Funding); Amgen – Consultant(Honoraria), Investigator(Grants/Research Funding); Apogee Therapeutics – Consultant (1099 relationship)(Honoraria), Other(Grants/Research Funding); Arcutis, Inc. – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Arena Pharmaceuticals – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Areteia Therapeutics – Other(Grants/Research Funding); Artax Biopharma – Other(Grants/Research Funding); Attovia Therapeutics – Investigator(Grants/Research Funding), Other(Grants/Research Funding); BioMimetix JV, LLC – Other(Grants/Research Funding); Bluefin Biomedicine – Other(Grants/Research Funding); BMS – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Brickell Biotech, Inc – Other(Grants/Research Funding); Cara Therapeutics – Other(Grants/Research Funding); Eli Lilly and Company – Advisory Board(Honoraria), Investigator(Grants/Research Funding); GSK – Consultant (1099 relationship)(Honoraria), Other(Grants/Research Funding); Horizon Therapeutics Ireland DAC – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Incyte Corporation – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Indero – Stockholder Private Company(Stock); Inmagene Biopharmaceuticals – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Janssen Scientific Affairs, LLC – Consultant(Honoraria), Investigator(Grants/Research Funding); Leo Pharma Inc – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Merck – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Nektar Therapeutics – Other(Grants/Research Funding); opsidio – Investigator(Grants/Research Funding); Opsidio – Other(Grants/Research Funding); Organon – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding), Other(Grants/Research Funding); Pelage Pharmaceuticals – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Pfizer Inc. – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Q32 Bio Inc. – Other(Grants/Research Funding); Sanofi – Other(Grants/Research Funding); Sanofi Aventis – Consultant(Honoraria); Sanofi Genzyme – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Sitryx – Consultant (1099 relationship)(Honoraria); Sun Pharmaceutical Industries Ltd. – Investigator(Grants/Research Funding); T-Rex BioPharma – Consultant (1099 relationship)(Honoraria); Takeda Development Center Americas, Inc. – Investigator(Grants/Research Funding); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria); TARGET Pharma – Consultant(Honoraria), Investigator(Grants/Research Funding); Triveni Bio – Other(Grants/Research Funding); UCB – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); VYNE Therapeutics – Other(Grants/Research Funding); Xencor – Investigator(Grants/Research Funding), Other(Grants/Research Funding); Zai Lab – Investigator(Grants/Research Funding); Zura Bio – Other(Grants/Research Funding);
Emma Guttman, MD, PhD, FAAD
AbbVie – Consultant(Fees), Consultant(Honoraria); Almirall – Consultant(Fees); Amgen – Consultant(Fees), Investigator(Grants/Research Funding); AnaptysBio – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); Apogee Therapeutics – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); Apollo Therapeutics Ltd – Investigator(Grants/Research Funding); Artax Biopharma – Consultant (1099 relationship)(Fees); Astria Therapeutics – Consultant (1099 relationship)(Fees); Bambusa Therapeutics Inc – Consultant (1099 relationship)(Fees); Biolojic Design – Consultant (1099 relationship)(Fees); Bionyra Pharma – Consultant (1099 relationship)(Fees); Boehringer Ingelheim – Consultant(Fees); Bristol-Myers Squibb – Advisory Board(Honoraria), Consultant(Fees); Celldex – Consultant (1099 relationship)(Fees); Cue Biopharma – Consultant (1099 relationship)(Fees); CytoReason – Consultant (1099 relationship)(Fees); DBV Technologies – Consultant (1099 relationship)(Fees); Dualitas Therapeutics – Consultant (1099 relationship)(Fees); Electra Therapeutics – Consultant (1099 relationship)(Fees); Eli Lilly and Company – Advisory Board(Honoraria), Consultant (1099 relationship)(Fees); EMD Serono – Consultant (1099 relationship)(Fees); Enveda Biosciences – Consultant (1099 relationship)(Fees); Evommune, Inc. – Consultant (1099 relationship)(Fees); Galderma Research & Development, LLC – Advisory Board(Honoraria), Consultant (1099 relationship)(Fees); Generate Biomedicines – Consultant (1099 relationship)(Fees); Gilead Sciences, Inc – Consultant (1099 relationship)(Fees); Incyte Corporation – Advisory Board(Honoraria), Consultant (1099 relationship)(Fees); Infimmune – Consultant (1099 relationship)(Fees); Inmagene Biopharmaceuticals – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); Janssen – Consultant (1099 relationship)(Fees); Jasper Therapeutics – Consultant (1099 relationship)(Fees); Kymera Therapeutics – Consultant (1099 relationship)(Fees); Kyowa Hakko Kirin Pharma, Inc. – Advisory Board(Honoraria), Consultant (1099 relationship)(Fees); Leo Pharma Inc – Advisory Board(Honoraria), Consultant(Fees), Investigator(Grants/Research Funding); Matchpoint Therapeutics – Consultant (1099 relationship)(Fees); Merck – Consultant(Fees), Consultant(Honoraria); Navigator Medicines – Consultant (1099 relationship)(Fees); Nektar Therapeutics – Consultant (1099 relationship)(Fees); Opsidio – Investigator(Grants/Research Funding); Pfizer Inc. – Advisory Board(Honoraria), Consultant(Fees), Investigator(Grants/Research Funding); Propeller Bio – Consultant (1099 relationship)(Fees); Proteologix US Inc – Consultant (1099 relationship)(Fees); RAPT Therapeutics – Consultant (1099 relationship)(Fees), Consultant (1099 relationship)(Honoraria), Consultant (1099 relationship)(Stock Options), Investigator(Grants/Research Funding); RayThera – Consultant (1099 relationship)(Fees); Regeneron – Advisory Board(Honoraria), Consultant(Fees), Investigator(Grants/Research Funding); Rubedo Life Sciences – Consultant (1099 relationship)(Fees); Sanofi – Advisory Board(Honoraria), Consultant(Fees), Investigator(Grants/Research Funding); SATO Pharmaceutical Co., Ltd – Consultant(Fees); Sitryx – Consultant (1099 relationship)(Fees); Sun Pharma Advanced Research Company (SPARC) – Consultant (1099 relationship)(Fees); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Fees); Teva – Consultant (1099 relationship)(Fees); TRex Bio – Consultant (1099 relationship)(Fees); Triveni Bio – Consultant (1099 relationship)(Fees); UCB – Consultant(Fees), Investigator(Grants/Research Funding); Ventyx Biosciences – Consultant (1099 relationship)(Fees); VeraDermics Inc. – Consultant (1099 relationship)(Fees); VRG Therapeutics – Consultant (1099 relationship)(Fees); Xencor – Consultant (1099 relationship)(Fees);
Iltefat H. Hamzavi, MD, FAAD
AbbVie – Advisory Board(Fees); Almirall – Consultant (1099 relationship)(Fees); Avita – Investigator(Grants/Research Funding); Beiersdorf, Inc. – Advisory Board(Fees); Boehringer Ingelheim – Consultant(Fees); Clinuvel – Investigator(Fees); Galderma Laboratories, L.P. – Investigator(Fees); Global Vitiligo Foundation – Board of Directors(No Compensation Received); Hidradenitis Suppurativa Foundation – Board of Directors(No Compensation Received); Incyte Corporation – Investigator(Grants/Research Funding); Janssen Biotech – Investigator(Grants/Research Funding); L'Oreal USA Inc. – Investigator(Grants/Research Funding); Lenicura – Investigator(Equipment); Merck – Investigator(Grants/Research Funding); MyDerm Portal, Inc – Stockholder(Stock); Novartis – Consultant(Fees); Pfizer Inc. – Investigator(Fees); Sonoma Biotherapeutics – Investigator(Grants/Research Funding); Takeda Pharmaceuticals USA Inc – Investigator(Grants/Research Funding); Teva Pharmaceutical Industries Ltd. – Investigator(Fees); UCB – Consultant(Fees); Union Therapeutics – Consultant(Fees); Vimela – Consultant (1099 relationship)(Fees);
Mark Lebwohl, MD, FAAD
AbbVie – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Added Health – Consultant (1099 relationship)(Honoraria); Aikium – Consultant (1099 relationship)(Honoraria); Almirall – Consultant(Honoraria); AltruBio Inc. – Consultant(Honoraria); Alumis – Consultant (1099 relationship)(Honoraria); Amgen – Consultant (1099 relationship)(Honoraria); Apogee Therapeutics – Consultant(Honoraria); Arcutis, Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); AstraZeneca – Consultant (1099 relationship)(Honoraria); Atomwise – Consultant(Honoraria); Avotres, Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); Boehringer Ingelheim – Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol Myers Squibb – Investigator(Grants/Research Funding); Bristol-Myers Squibb – Consultant(Honoraria); Cara Therapeutics – Investigator(Grants/Research Funding); Castle Biosciences, Inc – Consultant(Honoraria); Celltrion – Consultant(Honoraria); Clexio Biosciences, Ltd – Investigator(Grants/Research Funding); CoreEvitas, LLC – Consultant(Honoraria); Dermavant Sciences – Consultant(Honoraria), Investigator(Grants/Research Funding); Dermsquared – Consultant (1099 relationship)(Honoraria); Edesa Biotech – Consultant (1099 relationship)(Honoraria); Eli Lilly – Consultant (1099 relationship)(Honoraria); Eli Lilly and Company – Investigator(Grants/Research Funding); Evommune, Inc. – Consultant(Honoraria); Facilitation of International Dermatology Education – Consultant(Honoraria); Forte Biosciences – Consultant(Honoraria); Galderma – Consultant(Honoraria); Genentech, Inc. – Consultant(Honoraria); Incyte Corporation – Consultant(Honoraria), Investigator(Grants/Research Funding); Inozyme Pharma – Investigator(Grants/Research Funding); Janssen Research & Development, LLC – Investigator(Grants/Research Funding); Leo Pharma A/S – Consultant(Honoraria); Mayne Pharma Group – Consultant (1099 relationship)(Honoraria); Meiji Seika Pharma Co., Ltd – Consultant(Honoraria); Mindera – Consultant(Honoraria); Mirum Pharmaceuticals, Inc. – Consultant (1099 relationship)(Honoraria); MoonLake Immunotherapeutics – Consultant (1099 relationship)(Honoraria); New York College of Podiatric Medicine – Speaker/Faculty Education(Honoraria); Oruka Therapeutics – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); Revolo Therapeutics – Consultant (1099 relationship)(Honoraria); Sanofi/Regeneron – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Seanergy Maritime Holdings Corp. – Consultant(Honoraria); Strata Skin Sciences – Consultant(Honoraria); Sun Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Honoraria); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria); Teva Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Honoraria); Trevi Therapeutics – Consultant(Honoraria); UCB – Investigator(Grants/Research Funding); Verrica Pharmaceuticals Inc – Consultant(Honoraria);
Thierry Passeron, MD, PhD
AbbVie – Advisory Board(Honoraria), Speaker/Faculty Education(Honoraria); Almirall – Advisory Board(Honoraria); Amgen – Consultant(Honoraria); Astellas Pharma US, Inc – Investigator(Grants/Research Funding); Beiersdorf, Inc. – Speaker(Honoraria); Bioderma – Speaker/Faculty Education(Honoraria); Celgene Corporation – Investigator(Grants/Research Funding); Cutera, Inc. – Advisory Board(Honoraria); Galderma Research & Development, LLC – Advisory Board(Honoraria); GlaxoSmithKline – Speaker/Faculty Education(Honoraria); Hyphens Pharma – Speaker/Faculty Education(Honoraria); Incyte Corporation – Investigator(Fees), Speaker/Faculty Education(Honoraria); ISDIN – Advisory Board(Honoraria), Speaker(Honoraria); Janssen-Cilag – Advisory Board(Honoraria), Speaker/Faculty Education(Honoraria); Journal of the European Academy of Dermatology and Venereology – Other(No Compensation Received); L'Oréal Research and Innovation – Speaker/Faculty Education(Honoraria); La Roche-Posay Laboratorie Pharmaceutique – Speaker/Faculty Education(Honoraria); Leo Pharma Inc. – Speaker/Faculty Education(Honoraria); Lilly ICOS LLC – Speaker/Faculty Education(Honoraria); Mesoestetic USA Laboratories – Advisory Board(Honoraria); MSD – Advisory Board(Honoraria); Novartis – Advisory Board(Honoraria), Speaker(Honoraria); Pfizer Inc. – Advisory Board(Honoraria); Sanofi – Advisory Board(Honoraria); Sun Pharmaceutical Industries Ltd. – Speaker/Faculty Education(Honoraria); Symrise – Advisory Board(Honoraria); Takeda Pharmaceuticals USA Inc – Advisory Board(Honoraria); Vichy Laboratoires – Advisory Board(Honoraria), Speaker(Honoraria); VYNE Therapeutics – Advisory Board(Honoraria);
Bruce Elliot Strober, MD, PhD, FAAD
AbbVie – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); Alumis – Consultant(Fees); Amgen – Consultant (1099 relationship)(Fees); Arcutis, Inc. – Consultant(Fees), Speaker(Honoraria); Boehringer Ingelheim – Consultant(Honoraria); Bristol Myers Squibb – Speaker(Honoraria); Bristol-Myers Squibb – Advisory Board(Honoraria), Consultant(Fees); Connect Biopharma LLC – Stockholder(Other Financial Benefit); CoreEvitas, LLC – Advisory Board(Honoraria), Investigator(Fees); Eli Lilly and Company – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); Johnson and Johnson – Advisory Board(Honoraria), Consultant (1099 relationship)(Fees), Speaker(Honoraria); Leo Pharma Inc – Advisory Board(Honoraria), Consultant(Honoraria); Meiji Seika Pharma Co., Ltd – Consultant(Fees); Mindera – Stockholder(Other Financial Benefit); Novartis Pharmaceuticals Corp. – Advisory Board(Honoraria), Consultant(Honoraria); Oruka Therapeutics – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); UCB – Advisory Board(Honoraria), Consultant(Fees), Speaker(Honoraria);
Rolf-Markus Szeimies, MD, PhD, IFAAD
AbbVie – Speaker(Honoraria); Almirall – Advisory Board(Honoraria), Speaker(Honoraria); Beiersdorf, Inc. – Advisory Board(Fees); Biofrontera AG – Investigator(Fees), Speaker(Honoraria); Eli Lilly – Speaker(Honoraria); Galderma Laboratories, L.P. – Advisory Board(Honoraria), Investigator(Fees), Speaker(Honoraria); Janssen Pharmaceuticals, Inc – Speaker(Honoraria); Kurt Wolff GmbH & Co. KG – Advisory Board(Fees), Investigator(Fees); Leo Pharma A/S – Advisory Board(Honoraria), Investigator(Fees); Springer Publishing – Advisory Board(Honoraria);