S035 Psoriasis
DESCRIPTION
Join us for an exciting session packed with the latest developments in psoriasis therapies for 2025! You’ll learn about the evolving landscape of oral treatments, insights into managing GPP and palmoplantar pustulosis, advancements in precision medicine, and updates in psoriatic arthritis. Discover key pearls on topical therapies and the management of psoriatic nail disease. The session includes with two lively debates: (1) whether dermatologists should manage obesity in psoriasis patients, and (2) the ultimate showdown between oral therapies and biologics for moderate psoriasis. It will be Pso Pstimulating! This activity has been approved by the American Board of Dermatology (ABD) for up to 30 Continuing Certification Program (CCP) Component 2 Self-Assessment points. For more information about CCP, please visit the ABD website at www.abderm.org.
LEARNING OBJECTIVES
Discuss the practical use of topical, oral, and biologic therapies for the management of plaque psoriasis.
Debate (1) Should dermatologists manage obesity in psoriasis patients? (2) Oral versus biologics for the treatment of moderate plaque psoriasis
Discuss management of pustular psoriasis (GPP and PPP) and nail psoriasis.
SCHEDULE
1:00 PM
Welcome and Introduction
April W. Armstrong, MD, MPH, FAAD
1:05 PM
Hot Topics in Topical Therapies for Psoriasis in 2025
Erin E. Boh, MD, PhD, FAAD
1:20 PM
Evolving Landscape of Oral Therapies for Plaque Psoriasis
April W. Armstrong, MD, MPH, FAAD
1:35 PM
Therapeutic Pearls for Managing Generalized Pustular Psoriasis and Palmoplantar Pustulosis
Kristina Patrice Callis-Duffin, MD, FAAD
1:50 PM
Debate #1: Should dermatologists manage obesity in psoriasis patients?
Mark Lebwohl, MD, FAAD, Richard B Warren, MBChB, PhD
2:25 PM
Hot Topics in Biologic Therapies for Plaque Psoriasis in 2025
Bruce Elliot Strober, MD, PhD, FAAD
2:40 PM
Nail psoriasis or onychomycosis? Pearls on diagnosis and management of psoriatic nail disease
Boni E. Elewski, MD, FAAD
2:55 PM
Precision Medicine for Psoriatic Diseases and PsA Updates
Joseph Merola, MD, MSc, FAAD
3:10 PM
Debate #2: The Battle between Oral versus Biologics for the Treatment of Moderate Psoriasis
Kenneth B. Gordon, MD, FAAD, Richard G. B. Langley, MD, FAAD
3:45 PM
Curing Psoriasis?
Andrew Blauvelt, MD, FAAD
DIRECTOR
April W. Armstrong, MD, MPH, FAAD
SPEAKERS
Andrew Blauvelt, MD, FAAD
Erin E. Boh, MD, PhD, FAAD
Kristina Patrice Callis-Duffin, MD, FAAD
Boni E. Elewski, MD, FAAD
Kenneth B. Gordon, MD, FAAD
Richard G. B. Langley, MD, FAAD
Mark Lebwohl, MD, FAAD
Joseph Merola, MD, MSc, FAAD
Bruce Elliot Strober, MD, PhD, FAAD
Richard B Warren, MBChB, PhD
HANDOUTS
DISCLOSURES
April W. Armstrong, MD, MPH, FAAD
AbbVie – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Amgen – Advisory Board(Honoraria); Arcutis Biotherapeutics – Consultant(Honoraria); Boehringer Ingelheim – Data Safety Monitoring Board(Honoraria); Bristol-Myers Squibb – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Dermavant Sciences, Inc. – Consultant(Honoraria); Dermsquared – Advisory Board(Honoraria); Eli Lilly and Company – Advisory Board(Honoraria); Galderma USA – Advisory Board(Honoraria); Incyte – Consultant (1099 relationship)(Honoraria); Janssen Biotech – Consultant (1099 relationship)(Honoraria); Leo Pharma Inc – Consultant(Honoraria); Novartis – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Ortho Dermatologics – Speaker(Honoraria); Pfizer Inc. – Advisory Board(Honoraria); Regeneron – Advisory Board(Honoraria); Sanofi Genzyme – Consultant(Honoraria); Sun Pharmaceutical Industries Ltd. – Advisory Board(Honoraria); Takeda Pharmaceuticals USA Inc – Advisory Board(Honoraria), Investigator(Grants/Research Funding); UCB – Advisory Board(Honoraria);
Andrew Blauvelt, MD, FAAD
AbbVie – Consultant(Honoraria); Almirall – Consultant(Honoraria), Speaker(Honoraria); Alumis – Consultant (1099 relationship)(Honoraria); Amgen – Consultant (1099 relationship)(Honoraria); AnaptysBio – Consultant (1099 relationship)(Honoraria); Apogee Therapeutics – Consultant (1099 relationship)(Honoraria); Arcutis, Inc. – Consultant (1099 relationship)(Honoraria); Eli Lilly and Company – Consultant(Honoraria), Speaker(Honoraria); Incyte Corporation – Consultant(Honoraria); Janssen-Ortho Inc. – Consultant(Honoraria); Leo Pharma – Speaker(Honoraria); Leo Pharma Inc – Consultant(Honoraria); Lipidio Pharmaceuticals – Stockholder Private Company(Stock); Novartis Pharmaceuticals Corp. – Consultant(Honoraria); Oruka Therapeutics – Consultant (1099 relationship)(Honoraria), Stockholder Public Company(Stock); Pfizer Inc. – Consultant(Honoraria); Regeneron – Consultant(Honoraria); Sanofi – Consultant(Honoraria), Speaker(Honoraria); Sun Pharmaceutical Industries Ltd. – Consultant(Honoraria); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria); UCB – Consultant(Honoraria), Speaker(Honoraria);
Erin E. Boh, MD, PhD, FAAD
AbbVie – Investigator(Grants/Research Funding), Speaker(Honoraria); Arcutis Biotherapeutics – Advisory Board(Honoraria); BMS – Speaker(Honoraria); Boehringer Ingelheim – Speaker(Honoraria); Castle Biosciences – Investigator(Grants/Research Funding); Dermavant Sciences – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Dermira/Lilly – Investigator(Grants/Research Funding); Incyte Corporation – Investigator(Grants/Research Funding), Speaker(Honoraria); Janssen-Ortho Inc. – Investigator(Grants/Research Funding), Speaker(Honoraria); Ortho Dermatologics – Speaker(Honoraria); Pfizer Inc. – Investigator(Grants/Research Funding);
Kristina Patrice Callis-Duffin, MD, FAAD
AbbVie – Consultant(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria), Stockholder Public Company(No Compensation Received); Alumis – Investigator(Grants/Research Funding); Amgen – Advisory Board(Honoraria), Consultant(Honoraria); Boehringer Ingelheim – Advisory Board(Honoraria), Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol-Myers Squibb – Advisory Board(Honoraria), Consultant(Fees); Celgene Corporation – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Eli Lilly and Company – Consultant(Honoraria), Investigator(Grants/Research Funding); FIDE – Consultant (1099 relationship)(Honoraria); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Novartis – Consultant(Honoraria), Investigator(Grants/Research Funding); Oruka Therapeutics – Consultant (1099 relationship)(Honoraria); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); UCB – Stockholder Public Company(No Compensation Received);
Boni E. Elewski, MD, FAAD
AbbVie – Investigator(Grants/Research Funding); Amgen – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Boehringer Ingelheim – Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol-Myers Squibb – Investigator(Grants/Research Funding); Eli Lilly and Company – Investigator(Grants/Research Funding); Foundation for Research & Education of Dermatology – Advisory Board(Honoraria); Incyte Corporation – Investigator(Grants/Research Funding); Janssen Pharmaceuticals, Inc – Consultant (1099 relationship)(Honoraria); Janssen-Ortho Inc. – Investigator(Grants/Research Funding); Novartis Pharmaceuticals Corp. – Consultant(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); UCB – Consultant(Honoraria), Investigator(Grants/Research Funding);
Kenneth B. Gordon, MD, FAAD
AbbVie – Consultant(Honoraria), Investigator(Grants/Research Funding); Almirall – Consultant(Honoraria); Amgen – Consultant(Honoraria); Arcutis, Inc. – Consultant(Honoraria); Boehringer Ingelheim – Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol-Myers Squibb – Consultant(Honoraria); Dermavant Sciences – Consultant(Honoraria); Eli Lilly and Company – Investigator(Grants/Research Funding); Incyte Corporation – Consultant(Honoraria); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Leo Pharma Inc – Consultant(Honoraria); Lilly ICOS LLC – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria); Novartis Pharmaceuticals Corp. – Advisory Board(Honoraria); Othro Dermatologics – Consultant(Honoraria); Pfizer Inc. – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria); Protagonist Therapeutics – Consultant (1099 relationship)(Honoraria); Sanofi Genzyme – Consultant(Honoraria); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); UCB – Consultant(Honoraria);
Richard G. B. Langley, MD, FAAD
AbbVie – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Amgen – Investigator(Grants/Research Funding), Speaker(Honoraria); Boehringer Ingelheim – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Celgene Corporation – Advisory Board(Honoraria); Centocor Ortho Biotech Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Eli Lilly and Company – Advisory Board(Honoraria), Investigator(Honoraria); Genentech, Inc. – Investigator(Grants/Research Funding); LEO Laboratories Ltd (LEO Pharma) – Investigator(Grants/Research Funding); Merck Serono – Investigator(Grants/Research Funding); Novartis Pharmaceuticals Corp. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Investigator(Grants/Research Funding), Speaker(Honoraria); UCB – Advisory Board(Honoraria), Investigator(Grants/Research Funding);
Mark Lebwohl, MD, FAAD
AbbVie – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Added Health – Consultant (1099 relationship)(Honoraria); Aikium – Consultant (1099 relationship)(Honoraria); Almirall – Consultant(Honoraria); AltruBio Inc. – Consultant(Honoraria); Alumis – Consultant (1099 relationship)(Honoraria); Amgen – Consultant (1099 relationship)(Honoraria); Apogee Therapeutics – Consultant(Honoraria); Arcutis, Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); AstraZeneca – Consultant (1099 relationship)(Honoraria); Atomwise – Consultant(Honoraria); Avotres, Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); Boehringer Ingelheim – Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol Myers Squibb – Investigator(Grants/Research Funding); Bristol-Myers Squibb – Consultant(Honoraria); Cara Therapeutics – Investigator(Grants/Research Funding); Castle Biosciences, Inc – Consultant(Honoraria); Celltrion – Consultant(Honoraria); Clexio Biosciences, Ltd – Investigator(Grants/Research Funding); CoreEvitas, LLC – Consultant(Honoraria); Dermavant Sciences – Consultant(Honoraria), Investigator(Grants/Research Funding); Dermsquared – Consultant (1099 relationship)(Honoraria); Edesa Biotech – Consultant (1099 relationship)(Honoraria); Eli Lilly – Consultant (1099 relationship)(Honoraria); Eli Lilly and Company – Investigator(Grants/Research Funding); Evommune, Inc. – Consultant(Honoraria); Facilitation of International Dermatology Education – Consultant(Honoraria); Forte Biosciences – Consultant(Honoraria); Galderma – Consultant(Honoraria); Genentech, Inc. – Consultant(Honoraria); Incyte Corporation – Consultant(Honoraria), Investigator(Grants/Research Funding); Inozyme Pharma – Investigator(Grants/Research Funding); Janssen Research & Development, LLC – Investigator(Grants/Research Funding); Leo Pharma A/S – Consultant(Honoraria); Mayne Pharma Group – Consultant (1099 relationship)(Honoraria); Meiji Seika Pharma Co., Ltd – Consultant(Honoraria); Mindera – Consultant(Honoraria); Mirum Pharmaceuticals, Inc. – Consultant (1099 relationship)(Honoraria); MoonLake Immunotherapeutics – Consultant (1099 relationship)(Honoraria); New York College of Podiatric Medicine – Speaker/Faculty Education(Honoraria); Oruka Therapeutics – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); Revolo Therapeutics – Consultant (1099 relationship)(Honoraria); Sanofi/Regeneron – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Seanergy Maritime Holdings Corp. – Consultant(Honoraria); Strata Skin Sciences – Consultant(Honoraria); Sun Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Honoraria); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria); Teva Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Honoraria); Trevi Therapeutics – Consultant(Honoraria); UCB – Investigator(Grants/Research Funding); Verrica Pharmaceuticals Inc – Consultant(Honoraria);
Joseph Merola, MD, MSc, FAAD
AbbVie – Consultant(Honoraria); Amgen – Advisory Board(Honoraria); AstraZeneca – Consultant (1099 relationship)(Fees); Biogen – Consultant (1099 relationship)(Fees); Boehringer Ingelheim – Consultant (1099 relationship)(Fees); Bristol-Myers Squibb – Consultant (1099 relationship)(Fees); Eli Lilly and Company – Consultant(Honoraria); Galderma – Consultant (1099 relationship)(Fees); Janssen Pharmaceuticals, Inc – Consultant(Honoraria); MoonLake Immunotherapeutics – Consultant (1099 relationship)(Fees); Novartis – Consultant(Honoraria); Pfizer Inc. – Investigator(Fees); Sanofi/Regeneron – Consultant(Honoraria); Sun Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Fees); UCB – Consultant(Honoraria);
Bruce Elliot Strober, MD, PhD, FAAD
AbbVie – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); Alumis – Consultant(Fees); Amgen – Consultant (1099 relationship)(Fees); Arcutis, Inc. – Consultant(Fees), Speaker(Honoraria); Boehringer Ingelheim – Consultant(Honoraria); Bristol Myers Squibb – Speaker(Honoraria); Bristol-Myers Squibb – Advisory Board(Honoraria), Consultant(Fees); Connect Biopharma LLC – Stockholder(Other Financial Benefit); CoreEvitas, LLC – Advisory Board(Honoraria), Investigator(Fees); Eli Lilly and Company – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); Johnson and Johnson – Advisory Board(Honoraria), Consultant (1099 relationship)(Fees), Speaker(Honoraria); Leo Pharma Inc – Advisory Board(Honoraria), Consultant(Honoraria); Meiji Seika Pharma Co., Ltd – Consultant(Fees); Mindera – Stockholder(Other Financial Benefit); Novartis Pharmaceuticals Corp. – Advisory Board(Honoraria), Consultant(Honoraria); Oruka Therapeutics – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); UCB – Advisory Board(Honoraria), Consultant(Fees), Speaker(Honoraria);
Richard B Warren, MBChB, PhD
AbbVie – Investigator(Grants/Research Funding), Speaker/Faculty Education(Fees); Almirall – Investigator(Fees), Investigator(Grants/Research Funding); Amgen – Investigator(Honoraria), Speaker(Grants/Research Funding); Biogen – Investigator(Fees); BMS – Consultant(Honoraria), Investigator(Grants/Research Funding); Boehringer Ingelheim – Investigator(Fees); DICE Therapeutics – Consultant(Honoraria), Investigator(Grants/Research Funding); Eli Lilly and Company – Speaker(Honoraria); GSK – Investigator(Fees); Janssen-Cilag – Investigator(Grants/Research Funding), Speaker(Honoraria); Leo Foundation – Consultant(Honoraria), Investigator(Grants/Research Funding); Novartis – Investigator(Fees), Investigator(Grants/Research Funding); UCB – Investigator(Grants/Research Funding), Speaker(Honoraria); Union Therapeutics – Consultant(Honoraria), Investigator(Grants/Research Funding);